Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.