Photo of Dr. Namita Bhardwaj faculty physician at UTMB Health Family Medicine & Community Health

Namita Bhardwaj, MD, MS, MPH, CAQSM, FAAFP

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Kendall M. Campbell, MD, FAAFP - Chair of the UTMB Health Department of Family Medicine & Community Health

Kendall M. Campbell, MD, FAAFP

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Black and White photo of Ashley Collazo, MD, MPH

Ashley N. Collazo, MD, MPH

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Dr. Quratulanne "Annie" Jan faculty physician at UTMB Health Family Medicine & Community Health

Quratulanne Jan, MD, ACPA-C

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Dr. Oluwatosin Leshi Research Scientist at UTMB Health Family Medicine & Community Health

Oluwatosin O. Leshi, PhD MSc

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Samuel Mathis MD, MBA, Vice Chair of Clinical Operations UTMB Health Department of Family Medicine & Community Health

Samuel Mathis MD, MBA

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Ernst J. Nicanord, MD, Director of the UTMB Health Family Medicine & Community Health Residency Program

Ernst Nicanord, MD

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Dr. Courtney Ortz Research Scientist at UTMB Health Family Medicine & Community Health

Courtney L. Ortz, PhD, MSW

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Laura Porterfield, MD, MPH faculty physician with UTMB Health's Department of Family Medicine & Community Health

Laura Porterfield, MD, MPH

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Dr. Zuleica Santigo-Delgado faculty physician at UTMB Health Family Medicine & Community Health

Zuleica Santiago-Delgado, MD, FAAFP

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Dr. Brittany Smalls Vice Chair of Research UTMB Health Family Medicine & Community Health

Brittany Smalls, PhD, MSHA, MSHPsych

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Dr. Cathy Xie faculty physician at UTMB Health Family Medicine & Community Health

Cathy Xie, DO

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.

Photo of Dr. Hasan Yasin faculty physician at UTMB Health Family Medicine & Community Health

Hasan Yasin, MD

Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report

Stephanie Kim, Kyle Sheth, Xiaoying Yu, Laura Porterfield, Elizabeth M. Vaughan, Clinical course and treatment outcomes in solid-basaloid adenoid cystic carcinoma of the breast: A systematic review and case report, Cancer Treatment Reviews,
Volume 141, 2025, 103028, ISSN 0305-7372, https://doi.org/10.1016/j.ctrv.2025.103028.

(https://www.sciencedirect.com/science/article/pii/S0305737225001501)

Highlights

  • This systematic review examines clinical factors and outcomes in 134 SBACC patients from 19 studies and one new case.
  • Chemotherapy and immunotherapy showed poor outcomes, with no complete pathological response observed.
  • Younger age predicted recurrence, but chemotherapy had no effect on it; mastectomy and BCS had similar outcomes.
  • Poor chemo-immunotherapy response underscores the need for personalized treatment based on clinical and patient factors.