There's hope that a third shot of an mRNA vaccine—a so-called booster—will work better than two shots, says virologist Pei-Yong Shi at University of Texas Medical Branch in Galveston, who works with Pfizer. First off, he says, the third dose doesn't just return your antibody levels to what they were after the second shot. The level is even higher. On top of that, the booster can actually help broaden out your defenses so that you can fight off not just one variant of SARS-CoV-2 but many different versions of it. "The booster increases the level of antibodies that can push back against the variants," Shi says. "So that's another advantage to the booster."

Over the past two weeks, omicron has spread to at least seven of South Africa's nine provinces, quickly overtaking the country's outbreak—and thus, it appears, outcompeting delta, says virologist Pei-Yong Shi of the University of Texas Medical Branch in Galveston. “Based on the epidemiology data, it seems like the new variant has advantages in transmitting over the previous variants,” Shi said.

Dr. Pei-Yong Shi was referenced in the magazine’s coverage about the omicron variant.

Dr. Pei-Yong Shi discussed the new variant on Houston Matters, a radio program on Houston Public Media.

The University of Texas Medical Branch in Galveston will not enforce a vaccine requirement for its students and workforce, due to take effect Dec. 6, after a U.S. district judge granted a temporary injunction against a federal vaccine mandate for health care workers, UTMB announced Wednesday.

The speedy detection and the rapid response of global health authorities shows how the world’s fight against COVID-19 has evolved. Scientists are now focused on finding new variants. In the case of Omicron, one was beginning to spread in South Africa, a nation with the resources to identify it—and the political will to announce it to the world. Experiments using infectious virus or that tease out the effect of individual mutations on its behavior will take more time, but research that looks at the interactions between Omicron’s mutant spike and antibodies should yield some answers on the immune evasion question in as little as a week, said Vineet Menachery, a virologist at the University of Texas Medical Branch.