• Fireflies help kindle new tests and treatments for COVID-19

    This story from the Texas Medical Center focuses on Pei-Yong Shi’s work with the enzyme luciferase, which give lightning bugs their distinctive glow. Shi and his team are using the enzyme to develop faster and more accurate diagnostic tests for COVID-19. “The great thing about luciferase, and the one that we specifically use which is nanoluciferase, is that it’s really bright,” said fourth-year graduate student Coleman Baker.

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    Zika virus hijacks the host cell’s own defense mechanism to cause disease

    How did Zika virus acquire the ability to infect the brain and reproductive tissue to cause its characteristic disease? The answer may lie in a newly observed ability of the virus to use a host cell’s own defense mechanisms as a disguise. A team from The University of Texas Medical Branch at Galveston have published new research that shows the Zika virus evolved to use a host cellular enzyme for its own invasion, potentially explaining the mechanism by which the virus efficiently infects the brain and reproductive tissues, a potential explanation for how the Zika virus causes congenital neurological disorders like microcephaly, found in the newborns of infected mothers.

  • Tick Surveillance, control needed in the U.S., study shows

    A new national study concludes there is a clear need for more funding and coordination among tick surveillance programs across the country. The study cites UTMB’s Western Gulf Center of Excellence for Vector-Borne Diseases as a good program. The center performs research to expand surveillance for ticks and tick-borne pathogens. The center also trains future scientists and public health practitioners.

  • Post-COVID syndrome is a new, yet old, condition

    It is being reported that patients recovering from COVID-19 often experience after-effects such as fatigue, chest pain, rapid heartbeat, numbness, dizziness, gastrointestinal problems and more. Victor Sierpina explains this is not unheard of, noting that post-viral conditions have puzzled scientists and physicians for years.

  • UTMB researchers have discovered a new antiviral mechanism for dengue therapeutics

    Research conducted at UTMB has uncovered a new mechanism for designing antiviral drugs for dengue virus. Dengue virus is a mosquito-transmitted viral pathogen, causing 390 million human infections each year. “The World Health Organization lists dengue virus as one of the top ten public health threats and as such requires the urgent development of effective vaccine and therapeutics,” said Hongjie Xia, UTMB postdoctoral fellow and lead author of the study.

  • Building a COVID-19 vaccine

    This story from the Texas Medical Center examines the efforts undertaken to develop a COVID-19 vaccine. UTMB’s Alan Barret provides details on the many steps needed before a vaccine is determined effective and safe.

  • UTMB experts provide COVID-19 update

    UTMB’s Scott Weaver and Susan McLellan recently participated in a COVID-19 virtual update hosted by The Bay Area Houston Economic Partnership. The two experts discussed UTMB efforts to create antibody therapies and conduct clinical trials in the effort to develop a vaccine and mitigating the spread of the virus.

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