Microbiologist Pei-Yong Shi runs a high-containment laboratory at the University of Texas Medical Branch in Galveston. Over Thanksgiving, his team began engineering a replica of the new variant to test against the antibodies generated by vaccines. But it doesn’t happen overnight: It will take about two weeks to build the omicron replica, another few days to confirm that it’s an accurate facsimile, and one more week to pit the virus against blood samples from vaccinated people. “I think there is a lot of overreaction, and we just have to sit tight,” Shi said. “There are no results yet, these are just the mutations. What does that mean? We have to see.”