Publication of the Week - 08/08/2025

Title

Unraveling cerebrovascular involvement in EGPA through digital subtraction angiography: case presentation and systematic literature review

Authors

Viren Vasandani, Sean O'Leary, Ronak Gandhi, Elena Diller, Giri Movva, John Broussard, and Vijaya Murthy

Journal

BMC Rheumatology

Abstract

Eosinophilic granulomatosis with polyangiitis (EGPA) involves systemic inflammation of small to medium vessels, with central nervous system (CNS) involvement being rare. While CT (computed tomography) and MRI (magnetic resonance imaging) are standard for diagnosing CNS involvement, digital subtraction angiography (DSA) is infrequently used. We present a unique EGPA case with CNS involvement and review EGPA CNS vascular variations.