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Faculty Profile

Bio - Cuevas, Elvis, PhD

    • Q.F.B. Chemistry and Pharmacobiology, Faculty of Chemical Sciences. Benemérita Universidad Autónoma de Puebla, Puebla, Mexico

    • Ph.D. Neurobiology, Faculty of Biological Sciences, Universidad Nacional Autónoma de Mexico, CDMX, Mexico

    • Postdoctoral Fellow, ORISE. Division of Neurotoxicology, Laboratory of Neurochemistry, National Center for Toxicological Research, Food and Drug Administration, USA
    • Sex differences in neurodegenerative diseases, mainly in AD

    • Role of the blood-brain barrier in AD

    • Neurotoxicity in Neurodegenerative Diseases

    • Neuroinflammation in Neurodegenerative Diseases
    • Perez-Severiano F, Salvatierra-Sanchez R, Rodriguez-Perez M, Cuevas-Martinez EY, Guevara J, Limon D, Maldonado PD, Medina-Campos ON, Pedraza-Chaverri J, Santamaria A (2004) S-Allylcysteine prevents amyloid-beta peptide-induced oxidative stress in rat hippocampus and ameliorates learning deficits. Eur J Pharmacol 489, 197-202.

    • Cuevas E, Limon D, Perez-Severiano F, Diaz A, Ortega L, Zenteno E, Guevara J (2009) Antioxidant effects of epicatechin on the hippocampal toxicity caused by amyloid-beta 25-35 in rats. Eur J Pharmacol 616, 122-127.

    • Cuevas E, Lantz SM, Tobon-Velasco JC, Newport GD, Wu Q, Virmani A, Ali SF, Santamaria A (2011) On the in vivo early toxic properties of A-beta 25-35 peptide in the rat hippocampus: involvement of the Receptor-for-Advanced Glycation-End-Products and changes in gene expression. Neurotoxicol Teratol 33, 288-296.

    • Cuevas E, Rosas-Hernandez H, Burks SM, Ramirez-Lee MA, Guzman A, Imam SZ, Ali SF, Sarkar S (2019) Amyloid Beta 25-35 induces blood-brain barrier disruption in vitro. Metab Brain Dis 34, 1365-1374.

    • Gu Q, Cuevas E, Raymick J, Kanungo J, Sarkar S (2020) Downregulation of 14-3-3 Proteins in Alzheimer's Disease. Mol Neurobiol 57, 32-40.

    • Sarkar S, Raymick J, Cuevas E, Rosas-Hernandez H, Hanig J (2020) Modification of methods to use Congo-red stain to simultaneously visualize amyloid plaques and tangles in human and rodent brain tissue sections. Metab Brain Dis 35, 1371-1383.

    • Rosas-Hernandez H, Cuevas E, Raymick JB, Robinson BL, Sarkar S (2020) Impaired Amyloid Beta Clearance and Brain Microvascular Dysfunction are Present in the Tg-SwDI Mouse Model of Alzheimer's Disease. Neuroscience 440, 48-55.

    • Apatiga-Perez R, Soto-Rojas LO, Campa-Cordoba BB, Luna-Viramontes NI, Cuevas E, Villanueva-Fierro I, Ontiveros-Torres MA, Bravo-Munoz M, Flores-Rodriguez P, Garces-Ramirez L, de la Cruz F, Montiel-Sosa JF, Pacheco-Herrero M, Luna-Munoz J (2021) Neurovascular dysfunction and vascular amyloid accumulation as early events in Alzheimer's disease. Metab Brain Dis.
  • 2020NCTR Special act award
    2019NCTR Special act award
    2018Member of the Mexican SNI, Level 1, by CONACyT, Mexico
    2017 - 2018President of the Arkansas Chapter of the Society for Neuroscience
    2014Travel award to Workshop Collaborative zebrafish model
    2014Quality of Life Award, NCTR
    2008First Place in "Science Fair", as a PI, UNAM
  • 2020 - PresentInternational Society to Advance Alzheimer's Research and Treatment
    2010 - PresentArkansas Chapter of the Society for Neuroscience
    2002 - PresentSociety for Neuroscience