Faculty

Guy Nir, PhD Guy Nir, PhD

Assistant Professor, Department of Biochemistry & Molecular Biology

Tel: (409) 772-3575
E-mail: niguy@utmb.edu
Campus Location: 6.130 Medical Research Bldg
Mail Route: 0645

Pubmed Publications | Google Scholar | Lab Webpage

Research

Our lab’s field of research is genome organization, and how it may drive, or be driven by changes in gene expression. Our overarching goal is to modulate gene expression by changing the DNA sequence, so it affects the 3D structure of chromatin, which serves as a mechanism to regulate gene expression.

Structural and transcriptional reorganization which may regulate cell fate.
Structural and transcriptional reorganization which may regulate cell fate.

To that end we are using a variety of cutting-edge imaging technologies, molecular genetics, and computational approaches. With these single-cell technologies we are investigating how genome organization might be associated with transcriptional activity, and how together, they could influence cell fate.