Pathology Post Doctoral Program Directory

No imageRafael K Campos, PhD

Rafael K Campos, PhD

    • Molecular biology and pathogenesis of flaviviruses and alphaviruses
    • Alphavirus evolution in the mosquito host and vector-competence
    • Mechanisms of ZIKV persistent infection in testes
    • Vaccine development
    Present Postdoctoral Fellow

    Department of Microbiology and Immunology/Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
    Mentor: Drs Shannan Rossi and Scott Weaver.
    2018 PhD in Molecular Genetics and Microbiology

    Duke University, US.
    Advisors: Drs. Mariano Garcia-Blanco and Shelton Bradrick.
    2012 MS in Microbiology Universidade Federal de Minas Gerais (UFMG), Brazil.

    Advisor: Dr. Jonatas Santos Abrahao.
    2011 BS in Biology

    Pontifícia Universidade Católica de Minas Gerais (PUC-MG), Brazil.
  • 2019 Robert L. Harrison Poster Award at Pathology`s trainee research day, October 3rd.
    2019 James W. McLaughlin Travel Award, 29th March.
    2019 Committee member in a Master’s thesis defense of Gabriel Augusto Pires de Souza at UNIFAL-MG, Brazil.
    2018 Outstanding Poster Award. Awarded during UTMB retreat of the Biochemistry and Molecular Biology Department, 4 - 6 May.
    2013 PhD in Molecular Genetics and Microbiology Duke University, US.
    Advisors: Drs. Mariano Garcia-Blanco and Shelton Bradrick.
    2012 Best Master’s thesis of the Microbiology Department, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
    2010 Scientific merit, Best poster. Awarded during International Symposium – Smallpox Eradication After 30 Years: Lessons, Legacies and Innovations. Sabin Vaccine Institute, Fogarty International Center of the U.S. National Institutes of Health, and Fundação Oswaldo Cruz, 24 – 27 August. Rio de Janeiro, Brazil.
  • 2016 to Present - American Society for Virology

    Conferences and Presentations

    1. Apr 09 - 12, 2018. 6th Pan- American Dengue Research Network Meeting, Galveston, Texas Ribosomal Stalk proteins are required for efficient DENV translation elongation. (oral presentation).

    2. March 19 - 24, 2017. Gordon Research Conference - Translation Machinery in Health and Disease, Galveston, Texas. Identification of ribosomal stalk proteins that are essential for translation of flavivirus genomes. (oral presentation).

    3. June 18-22, 2016. 35th Annual meeting of American Society of Virology, Blacksburg, Virginia. RPLP1 and RPLP2 are Critical Flavivirus Host Factors Required for Efficient Viral Translation (oral presentation).

  • 1.Campos RK, Preciado-Llanes L, Azar SR, Lopez-Camacho C, Reyes-Sandoval A, Rossi SL. (2019) A Single and Un-Adjuvanted Dose of a Chimpanzee Adenovirus-Vectored Vaccine. against Chikungunya Virus Fully Protects Mice from Lethal Disease. Pathogens 1,  ;8(4). pii: E231.

    2. Hanley KA, Azar SR, Campos RK, Vasilakis N, Rossi SL. (2019). Support for the Transmission-Clearance Trade-Off Hypothesis from a Study of Zika Virus Delivered by Mosquito Bite to Mice. Viruses 11(11). pii: E1072.

    3. Barrows NJ, Campos RK, Liao KC, Prasanth KR, Soto-Acosta R, Yeh SC, Schott-Lerner G, Pompon J, Sessions OM, Bradrick SS, Garcia-Blanco MA.(2018)  Biochemistry and Molecular Biology of Flaviviruses. Chem Rev 118, 4448- 4482.

    4. Reid DW, Campos RK, Child JR, Zheng T, Chand KWK, Bradrick SS, Vasudevand SG, Garcia-Blanco MA, and Nicchitta CV. (2018). Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis. J Virol. 92, e01766-1.

    5. Campos R.K., Wong B., Xie X., Lu Y.F., Shi P.Y., Pompon J., Garcia-Blanco M.A., Bradrick S.S.(2017). RPLP1 and RPLP2 Are Essential Flavivirus Host Factors That Promote Early Viral Protein Accumulation. J Virol 91, pii:e01706-16.

    6. Campos RK, Garcia-Blanco MA, Bradrick SS. (2017). Roles of Pro-viral Host Factors in Mosquito-Borne Flavivirus Infections. Curr Top Microbiol Immunol 419, 43-67, 2017

    7. Barrows NJ, Campos RK, Powell ST, Prasanth KR, Schott-Lerner G, Soto-Acosta R, Galarza-Muñoz G, McGrath EL, Urrabaz-Garza R, Gao J, Wu P, Menon R, Saade G, Fernandez-Salas I, Rossi SL, Vasilakis N, Routh A, Bradrick SS, Garcia-Blanco MA. (2016). A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection. Cell Host Microbe. 20, 259-70.

    8. Abrahão JS, Campos RK, Trindade Gde S, Guimarães da Fonseca F, Ferreira PC, Kroon EG. Outbreak of  severe zoonotic vaccinia virus infection, Southeastern Brazil. (2015) Emerg Infect Dis 21(4), 695-8.

    9. Campos, R.K., Boratto, P.V., Assis, F.L., Aguiar, E.R., Silva, L.C., Albarnaz, J.D., Dornas, F.P., Trindade, G.S., Ferreira, P.P., Marques, J.T., Robert, C., Raoult, D., Kroon, E.G., La Scola, B., Abrahão, J.S. (2014). Samba virus: a novel mimivirus from a giant rain forest, the Brazilian Amazon. Virol J. 11, 95.

    10. Silva, L.C., Almeida, G.M., Oliveira, D.B., Dornas, F.P., Campos, R.K., La Scola, B., Ferreira, P.C., Kroon, E.G., Abrahão, J.S. (2014). A resourceful giant: APMV is able to interfere with the human type I interferon system. Microbes Infect. 16,187-95.

    11. Dornas, F.P., Silva, L.C., de Almeida, G.M., Campos, R.K., Boratto, P.V., Franco-Luiz, A.P., La Scola, B., Ferreira, P.C., Kroon, E.G., Abrahão, J.S. (2014). Acanthamoeba polyphaga mimivirus stability in environmental and clinical substrates: implications for virus detection and isolation. Plos one 9, e87811.

    12. Abrahão, J.S., Boratto, P., Dornas, F.P., Silva, L.C., Campos, R.K., Almeida, G.M., Kroon, E.G., La Scola, B. (2014). Growing a giant: evaluation of the virological parameters for mimivirus production. J Virol Methods. 207, 6-11.

    13. Oliveira, D.B., Campos, R.K., Soares, M.S., Barros, R.B., Batista, T.C., >Ferreira, P.C., Bonjardim, C.A., Trindade, G.S., Abrahão, J.S., Kroon, E.G. (2014) Outbreak of herpangina in the Brazilian Amazon in 2009 caused by Enterovirus B. Arch Virol. 159, 1155-7.

    14. Silva, L.C., Almeida, G.M., Oliveira, D.B., Dornas, F.P., Campos, R.K., La Scola, B., Ferreira, P.C., Kroon, E.G., Abrahão, J.S. (2014). A resourceful giant: APMV is able to interfere with the human type I interferon system. Microbes Infect. 16, 187-95.

    15. Campos, R.K., Andrade, K.R., Ferreira, P.C., Bonjardim, C.A., La Scola, B., Kroon, E.G., Abrahão, J.S. (2012) Virucidal activity of chemical biocides against mimivirus, a putative pneumonia agent. J Clin Virol. 55, 323-8..

    16. Assis FL, Almeida GM, Oliveira DB, Franco-Luiz AP, Campos RK, Guedes MI, Fonseca FG, Trindade GS, Drumond BP, Kroon EG, Abrahão JS. (2012). Characterization of a new Vaccinia virus isolate reveals the C23L gene as a putative genetic marker for autochthonous Group 1 Brazilian Vaccinia virus. PLoS One. 7(11), e50413.

    17. Campos, R.K., Brum, M.C.S., Nogueira, C.E.W., Drumond, B.P., Alves, P.A., Siqueira-Lima, L.,Assis, F.L., Trindade, G.S., Bonjardim, C.A., Ferreira, P.C., Weiblen, R., Flores, E.F., Kroon, E.G., Abrahão, J.S (2011). Assessing the variability of Brazilian Vaccinia virus isolates from a horse exanthematic lesion: coinfection with distinct viruses. Arch. Virol. 156, 275-283.

    18. Abrahão, J.S., Drumond, B.P., de Souza Trindade, G., da Silva-Fernandes, A.T., Ferreira, J.M.S.,Alves, P.A., Campos, R.K., Siqueira, L., Bonjardim, C.A., Ferreira, P.C.P., Kroon, E.G. (2010). Rapid detection of Orthopoxvirus by semi-nested PCR directly from clinical specimens: A useful alternative for routine laboratories J. Med. Virol. 82, 692-699.

    19. de Oliveira, T.M.L., Rehfeld, I.S., Siqueira, J.M.F., Abrahão, J.S., Campos, R.K., dos Santos, A.K.R., Cerqueira, M.M.O.P., Kroon, E.G., Lobato, Z.I.P. (2010). Vaccinia virus is not inactivated after thermal treatment and cheese production using experimentally contaminated milk. Foodborne Pathog. Dis. 7, 1491-1496.

    20. Abrahão, J.S., Oliveira, T.M.L., Campos, R.K., Madureira, M.C., Kroon, E.G., Lobato, Z.I.P. (2009). Bovine Vaccinia outbreaks: detection and isolation of Vaccinia Virus in milk samples. Foodborne Pathog. Dis. 6, 1141- 1146.

    21. Abrahão, J.S., Campos, R.K., Trindade, G.S., Guedes, M.I., Lobato, Z.I.P., Mazur, C., Peregrino, P.C., Bonjardim, C.A., Kroon, E.G. (2009). Detection and phylogenetic analysis of Orf virus from sheep in Brazil: Case Report. Virol. J. 6, 47.

    22. Abrahão, J.S., Trindade, G.S., Ferreira, J.M.S., Campos, R.K., Bonjardim, C.A., Ferreira, P.C.P., Kroon,E.G. (2009). Long-lasting stability of Vaccinia virus strains in murine feces: implications for virus circulation and environmental maintenance. Arch. Virol. 154, 1551-1553.

    23. Abrahão, J.S., Lima, L., Assis, F.L., Alves, P.A., Silva-Fernandes, A.T., Cota, M., Ferreira, V.M., Campos, R.K., Mazur, C., Lobato, Z.I.P., Trindade, G.S., Kroon, E.G. (2009). Nested-multiplex PCR detection of Orthopoxvirus and Parapoxvirus directly from exanthematic clinical samples. Virol.J 6, 140.

    24. Abrahão, J.S., Guedes, M.I., Trindade, G.S., Fonseca, F.G., Campos, R.K., Mota, B.E.F., Lobato, Z.I.P., Silva-Fernandes, A.T., Rodrigues, G.O., Lima, L.S., Ferreira, P.C., Bonjardim, C.A., Kroon, E.G. (2009). One more piece in the VACV ecological puzzle: could peridomestic rodents be the link between wildlife and bovine vaccinia outbreaks in Brazil? Plos One 4, e7428-e7428.