The Rossi Lab

2023

Campos RK, Rossi SL, Tesh RB, Weaver SC. Zoonotic mosquito-borne arboviruses: Spillover, spillback, and realistic mitigation strategies. Sci Transl Med. 2023 Oct 18;15(718):eadj2166. doi: 10.1126/scitranslmed.adj2166. Epub 2023 Oct 18. PMID: 37851824.

Ly J, Campos RK, Hager-Soto EE, Camargos VN, Rossi SL. Testicular pathological alterations associated with SARS-CoV-2 infection. Front Reprod Health. 2023 Jun 29;5:1229622. doi: 10.3389/frph.2023.1229622. PMID: 37457430; PMCID: PMC10338913.

Hanley KA, Cecilia H, Azar SR, Moehn B, Yu W, Yun R, Althouse BM, Vasilakis N, Rossi SL. Immunologically mediated trade-offs shaping transmission of sylvatic dengue and Zika viruses in native and novel non-human primate hosts. bioRxiv [Preprint]. 2023 Jun 30:2023.06.30.547187. doi: 10.1101/2023.06.30.547187. PMID: 37425901; PMCID: PMC10327119.

Cao X, Yang D, Parvathareddy J, Chu YK, Kim EJ, Fitz-Henley JN, Li X, Lukka PB, Parmar KR, Temrikar ZH, Dhole P, Adcock RS, Gabbard J, Bansal S, Lee J, Zalduondo L, Hayes E, Stabenow J, Meibohm B, Fitzpatrick EA, Bailey K, Campos RK, Julander JG, Rossi SL, Chung D, Jonsson CB, Golden JE. Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models. Sci Transl Med. 2023 Apr 12;15(691):eabl9344. doi: 10.1126/scitranslmed.abl9344. Epub 2023 Apr 12. PMID: 37043558.


2022

Monath TP, Nichols R, Tussey L, Scappaticci K, Pullano TG, Whiteman MD, Vasilakis N, Rossi SL, Campos RK, Azar SR, Spratt HM, Seaton BL, Archambault WT, Costecalde YV, Moore EH, Hawks RJ, Fusco J. Recombinant vesicular stomatitis vaccine against Nipah virus has a favorable safety profile: Model for assessment of live vaccines with neurotropic potential. PLoS Pathog. 2022 Jun 27;18(6):e1010658. doi: 10.1371/journal.ppat.1010658. PMID: 35759511; PMCID: PMC9269911.

Azar SR, Campos RK, Yun R, Strange T, Rossi SL, Hanley KA, Vasilakis N, Weaver SC. Aedes aegypti Shows Increased Susceptibility to Zika Virus via Both In Vitro and In Vivo Models of Type II Diabetes. Viruses. 2022 Mar 23;14(4):665. doi: 10.3390/v14040665. PMID: 35458395; PMCID: PMC9024453.

Haines CA, Campos RK, Azar SR, Warmbrod KL, Kautz TF, Forrester NL, Rossi SL. Venezuelan Equine Encephalitis Virus V3526 Vaccine RNA-Dependent RNA Polymerase Mutants Increase Vaccine Safety Through Restricted Tissue Tropism in a Murine Model. Zoonoses (Burlingt). 2022;2:2. doi: 10.15212/zoonoses-2021-0016. Epub 2022 Jan 13. PMID: 35262074; PMCID: PMC8900488.


2021

Xiao J, Zhang B, Su Z, Liu Y, Shelite TR, Chang Q, Qiu Y, Bei J, Wang P, Bukreyev A, Soong L, Jin Y, Ksiazek T, Gaitas A, Rossi SL, Zhou J, Laposata M, Saito TB, Gong B. Intracellular receptor EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K-/eNOS-dependent manner during inflammation. J Biol Chem. 2021 Nov;297(5):101315. doi: 10.1016/j.jbc.2021.101315. Epub 2021 Oct 20. PMID: 34678311; PMCID: PMC8526113.

Folegatti PM, Harrison K, Preciado-Llanes L, Lopez FR, Bittaye M, Kim YC, Flaxman A, Bellamy D, Makinson R, Sheridan J, Azar SR, Campos RK, Tilley M, Tran N, Jenkin D, Poulton I, Lawrie A, Roberts R, Berrie E, Rossi SL, Hill A, Ewer KJ, Reyes-Sandoval A. A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial. Nat Commun. 2021 Jul 30;12(1):4636. doi: 10.1038/s41467-021-24906-y. PMID: 34330906; PMCID: PMC8324904.

Campos RK, Camargos VN, Azar SR, Haines CA, Eyzaguirre EJ, Rossi SL. SARS-CoV-2 Infects Hamster Testes. Microorganisms. 2021 Jun 17;9(6):1318. doi: 10.3390/microorganisms9061318. PMID: 34204370; PMCID: PMC8235703.

Xu P, Shan C, Dunn TJ, Xie X, Xia H, Gao J, Labastida JA, Jing Z, Villarreal PP, Schlagal CR, Yu Y, Vargas G, Rossi SL, Vasilakis N, Shi PY, Weaver SC, Wu P. Correction: Role of microglia in the dissemination of Zika virus from mother to fetal brain. PLoS Negl Trop Dis. 2021 Apr 13;15(4):e0009344. doi: 10.1371/journal.pntd.0009344. Erratum for: PLoS Negl Trop Dis. 2020 Jul 6;14(7):e0008413. PMID: 33848289; PMCID: PMC8043386.


2020

Read CM, Plante K, Rafael G, Rossi SL, Braun W, Weaver SC, Schein CH. Designing multivalent immunogens for alphavirus vaccine optimization. Virology. 2021 Sep;561:117-124. doi: 10.1016/j.virol.2020.11.010. Epub 2021 Feb 5. PMID: 33823988; PMCID: PMC8277671.

Campos RK, Preciado-Llanes L, Azar SR, Kim YC, Brandon O, López-Camacho C, Reyes-Sandoval A, Rossi SL. Adenoviral-Vectored Mayaro and Chikungunya Virus Vaccine Candidates Afford Partial Cross-Protection From Lethal Challenge in A129 Mouse Model. Front Immunol. 2020 Nov 4;11:591885. doi: 10.3389/fimmu.2020.591885. PMID: 33224148; PMCID: PMC7672187.

Scroggs SLP, Gass JT, Chinnasamy R, Widen SG, Azar SR, Rossi SL, Arterburn JB, Vasilakis N, Hanley KA. Evolution of resistance to fluoroquinolones by dengue virus serotype 4 provides insight into mechanism of action and consequences for viral fitness. Virology. 2021 Jan 2;552:94-106. doi: 10.1016/j.virol.2020.09.004. Epub 2020 Oct 1. PMID: 33120225; PMCID: PMC7528753.

Scroggs SLP, Andrade CC, Chinnasamy R, Azar SR, Schirtzinger EE, Garcia EI, Arterburn JB, Hanley KA, Rossi SL. Old Drugs with New Tricks: Efficacy of Fluoroquinolones to Suppress Replication of Flaviviruses. Viruses. 2020 Sep 13;12(9):1022. doi: 10.3390/v12091022. PMID: 32933138; PMCID: PMC7551155.

Xiao J, Zhang B, Su Z, Liu Y, Shelite TR, Chang Q, Wang P, Bukreyev A, Soong L, Jin Y, Ksiazek T, Gaitas A, Rossi SL, Zhou J, Laposata M, Saito TB, Gong B. EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K/eNOS-dependent manner during inflammation. bioRxiv [Preprint]. 2020 Sep 4:2020.09.04.282806. doi: 10.1101/2020.09.04.282806. Update in: J Biol Chem. 2021 Nov;297(5):101315. PMID: 32908983; PMCID: PMC7480044.

Rossi SL, Russell-Lodrigue KE, Plante KS, Bergren NA, Gorchakov R, Roy CJ, Weaver SC. Rationally Attenuated Vaccines for Venezuelan Equine Encephalitis Protect Against Epidemic Strains with a Single Dose. Vaccines (Basel). 2020 Sep 2;8(3):497. doi: 10.3390/vaccines8030497. PMID: 32887313; PMCID: PMC7563393.

Azar SR, Campos RK, Bergren NA, Camargos VN, Rossi SL. Epidemic Alphaviruses: Ecology, Emergence and Outbreaks. Microorganisms. 2020 Aug 1;8(8):1167. doi: 10.3390/microorganisms8081167. PMID: 32752150; PMCID: PMC7464724.

Shan C, Xia H, Haller SL, Azar SR, Liu Y, Liu J, Muruato AE, Chen R, Rossi SL, Wakamiya M, Vasilakis N, Pei R, Fontes-Garfias CR, Singh SK, Xie X, Weaver SC, Shi PY. A Zika virus envelope mutation preceding the 2015 epidemic enhances virulence and fitness for transmission. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20190-20197. doi: 10.1073/pnas.2005722117. Epub 2020 Aug 3. PMID: 32747564; PMCID: PMC7443865.

Giraldo MI, Xia H, Aguilera-Aguirre L, Hage A, van Tol S, Shan C, Xie X, Sturdevant GL, Robertson SJ, McNally KL, Meade-White K, Azar SR, Rossi SL, Maury W, Woodson M, Ramage H, Johnson JR, Krogan NJ, Morais MC, Best SM, Shi PY, Rajsbaum R. Envelope protein ubiquitination drives entry and pathogenesis of Zika virus. Nature. 2020 Sep;585(7825):414-419. doi: 10.1038/s41586-020-2457-8. Epub 2020 Jul 8. PMID: 32641828; PMCID: PMC7501154.

Xu P, Shan C, Dunn TJ, Xie X, Xia H, Gao J, Allende Labastida J, Zou J, Villarreal PP, Schlagal CR, Yu Y, Vargas G, Rossi SL, Vasilakis N, Shi PY, Weaver SC, Wu P. Role of microglia in the dissemination of Zika virus from mother to fetal brain. PLoS Negl Trop Dis. 2020 Jul 6;14(7):e0008413. doi: 10.1371/journal.pntd.0008413. Erratum in: PLoS Negl Trop Dis. 2021 Apr 13;15(4):e0009344. PMID: 32628667; PMCID: PMC7365479.

Luo H, Li G, Wang B, Tian B, Gao J, Zou J, Shi S, Zhu S, Peng BH, Adam A, Martinez A, Hein K, Winkelmann ER, Mahmoud Y, Zhou X, Shan C, Rossi S, Weaver S, Barrett ADT, Sun SC, Zhang W, Shi PY, Wu P, Wang T. Peli1 signaling blockade attenuates congenital zika syndrome. PLoS Pathog. 2020 Jun 16;16(6):e1008538. doi: 10.1371/journal.ppat.1008538. PMID: 32544190; PMCID: PMC7297310.

Liu Y, Xiao J, Zhang B, Shelite TR, Su Z, Chang Q, Judy B, Li X, Drelich A, Bei J, Zhou Y, Zheng J, Jin Y, Rossi SL, Tang SJ, Wakamiya M, Saito T, Ksiazek T, Kaphalia B, Gong B. Increased talin-vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections. Lab Invest. 2020 Aug;100(8):1030-1041. doi: 10.1038/s41374-020-0420-9. Epub 2020 Apr 1. PMID: 32238906; PMCID: PMC7111589.

Tretyakova I, Plante KS, Rossi SL, Lawrence WS, Peel JE, Gudjohnsen S, Wang E, Mirchandani D, Tibbens A, Lamichhane TN, Lukashevich IS, Comer JE, Weaver SC, Pushko P. Venezuelan equine encephalitis vaccine with rearranged genome resists reversion and protects non-human primates from viremia after aerosol challenge. Vaccine. 2020 Apr 9;38(17):3378-3386. doi: 10.1016/j.vaccine.2020.02.007. Epub 2020 Feb 19. PMID: 32085953.

Jain J, Kaur N, Haller SL, Kumar A, Rossi SL, Narayanan V, Kumar D, Gaind R, Weaver SC, Auguste AJ, Sunil S. Chikungunya Outbreaks in India: A Prospective Study Comparing Neutralization and Sequelae during Two Outbreaks in 2010 and 2016. Am J Trop Med Hyg. 2020 Apr;102(4):857-868. doi: 10.4269/ajtmh.19-0481. PMID: 32067624; PMCID: PMC7124918.

Bergren NA, Haller S, Rossi SL, Seymour RL, Huang J, Miller AL, Bowen RA, Hartman DA, Brault AC, Weaver SC. "Submergence" of Western equine encephalitis virus: Evidence of positive selection argues against genetic drift and fitness reductions. PLoS Pathog. 2020 Feb 6;16(2):e1008102. doi: 10.1371/journal.ppat.1008102. PMID: 32027727; PMCID: PMC7029877.


2019

Webb EM, Azar SR, Haller SL, Langsjoen RM, Cuthbert CE, Ramjag AT, Luo H, Plante K, Wang T, Simmons G, Carrington CVF, Weaver SC, Rossi SL, Auguste AJ. Effects of Chikungunya virus immunity on Mayaro virus disease and epidemic potential. Sci Rep. 2019 Dec 31;9(1):20399. doi: 10.1038/s41598-019-56551-3. PMID: 31892710; PMCID: PMC6938517.

Hanley KA, Azar SR, Campos RK, Vasilakis N, Rossi SL. Support for the Transmission-Clearance Trade-Off Hypothesis from a Study of Zika Virus Delivered by Mosquito Bite to Mice. Viruses. 2019 Nov 18;11(11):1072. doi: 10.3390/v11111072. PMID: 31752097; PMCID: PMC6893444.

Campos RK, Preciado-Llanes L, Azar SR, Lopez-Camacho C, Reyes-Sandoval A, Rossi SL. A Single and Un-Adjuvanted Dose of a Chimpanzee Adenovirus-Vectored Vaccine against Chikungunya Virus Fully Protects Mice from Lethal Disease. Pathogens. 2019 Nov 12;8(4):231. doi: 10.3390/pathogens8040231. PMID: 31718104; PMCID: PMC6963200.

Johnson BA, Hage A, Kalveram B, Mears M, Plante JA, Rodriguez SE, Ding Z, Luo X, Bente D, Bradrick SS, Freiberg AN, Popov V, Rajsbaum R, Rossi S, Russell WK, Menachery VD. Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity. J Virol. 2019 Oct 29;93(22):e01282-19. doi: 10.1128/JVI.01282-19. PMID: 31462558; PMCID: PMC6819921.

Estofolete CF, de Oliveira Mota MT, Bernardes Terzian AC, de Aguiar Milhim BHG, Ribeiro MR, Nunes DV, Mourão MP, Rossi SL, Nogueira ML, Vasilakis N. Unusual clinical manifestations of dengue disease - Real or imagined? Acta Trop. 2019 Nov;199:105134. doi: 10.1016/j.actatropica.2019.105134. Epub 2019 Aug 12. PMID: 31415737.

Rossi SL, Comer JE, Wang E, Azar SR, Lawrence WS, Plante JA, Ramsauer K, Schrauf S, Weaver SC. Immunogenicity and Efficacy of a Measles Virus-Vectored Chikungunya Vaccine in Nonhuman Primates. J Infect Dis. 2019 Jul 31;220(5):735-742. doi: 10.1093/infdis/jiz202. PMID: 31053842; PMCID: PMC6667792.

Dora EG, Rossi SL, Weaver SC, Tucker SN, Mateo R. An adjuvanted adenovirus 5-based vaccine elicits neutralizing antibodies and protects mice against chikungunya virus-induced footpad swelling. Vaccine. 2019 May 27;37(24):3146-3150. doi: 10.1016/j.vaccine.2019.04.069. Epub 2019 Apr 29. PMID: 31047675.

Rodriguez-Barraquer I, Costa F, Nascimento EJM, Nery N Júnior, Castanha PMS, Sacramento GA, Cruz J, Carvalho M, De Olivera D, Hagan JE, Adhikarla H, Wunder EA Jr, Coêlho DF, Azar SR, Rossi SL, Vasilakis N, Weaver SC, Ribeiro GS, Balmaseda A, Harris E, Nogueira ML, Reis MG, Marques ETA, Cummings DAT, Ko AI. Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region. Science. 2019 Feb 8;363(6427):607-610. doi: 10.1126/science.aav6618. PMID: 30733412; PMCID: PMC8221194.


2018

Soto-Acosta R, Xie X, Shan C, Baker CK, Shi PY, Rossi SL, Garcia-Blanco MA, Bradrick S. Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA. Elife. 2018 Dec 4;7:e39023. doi: 10.7554/eLife.39023. PMID: 30511641; PMCID: PMC6279352.

Azar SR, Rossi SL, Haller SH, Yun R, Huang JH, Plante JA, Zhou J, Olano JP, Roundy CM, Hanley KA, Weaver SC, Vasilakis N. ZIKV Demonstrates Minimal Pathologic Effects and Mosquito Infectivity in Viremic Cynomolgus Macaques. Viruses. 2018 Nov 21;10(11):661. doi: 10.3390/v10110661. PMID: 30469417; PMCID: PMC6267344.

Xie X, Kum DB, Xia H, Luo H, Shan C, Zou J, Muruato AE, Medeiros DBA, Nunes BTD, Dallmeier K, Rossi SL, Weaver SC, Neyts J, Wang T, Vasconcelos PFC, Shi PY. A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission. Cell Host Microbe. 2018 Oct 10;24(4):487-499.e5. doi: 10.1016/j.chom.2018.09.008. PMID: 30308155; PMCID: PMC6188708.

Rossi SL, Ebel GD, Shan C, Shi PY, Vasilakis N. Did Zika Virus Mutate to Cause Severe Outbreaks? Trends Microbiol. 2018 Oct;26(10):877-885. doi: 10.1016/j.tim.2018.05.007. Epub 2018 Jun 11. PMID: 29903417; PMCID: PMC6160291.

Langsjoen RM, Haller SL, Roy CJ, Vinet-Oliphant H, Bergren NA, Erasmus JH, Livengood JA, Powell TD, Weaver SC, Rossi SL. Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models. mBio. 2018 Mar 6;9(2):e02449-17. doi: 10.1128/mBio.02449-17. PMID: 29511072; PMCID: PMC5844994.

Koma T, Veljkovic V, Anderson DE, Wang LF, Rossi SL, Shan C, Shi PY, Beasley DW, Bukreyeva N, Smith JN, Hallam S, Huang C, von Messling V, Paessler S. Zika virus infection elicits auto-antibodies to C1q. Sci Rep. 2018 Jan 30;8(1):1882. doi: 10.1038/s41598-018-20185-8. PMID: 29382894; PMCID: PMC5789871.

Rossi SL, Estofolete CF, Nogueira ML, Vasilakis N. Age and Sex in the Zika Pandemic Era. J Infect Dis. 2018 May 5;217(11):1675-1677. doi: 10.1093/infdis/jix631. PMID: 29216367; PMCID: PMC5946828.

Vanchiere JA, Ruiz JC, Brady AG, Kuehl TJ, Williams LE, Baze WB, Wilkerson GK, Nehete PN, McClure GB, Rogers DL, Rossi SL, Azar SR, Roundy CM, Weaver SC, Vasilakis N, Simmons JH, Abee CR. Experimental Zika Virus Infection of Neotropical Primates. Am J Trop Med Hyg. 2018 Jan;98(1):173-177. doi: 10.4269/ajtmh.17-0322. Epub 2018 Jan 1. PMID: 29182145; PMCID: PMC5928705.


2017

Chen J, Liang Y, Yi P, Xu L, Hawkins HK, Rossi SL, Soong L, Cai J, Menon R, Sun J. Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action. Cell Rep. 2017 Nov 7;21(6):1588-1599. doi: 10.1016/j.celrep.2017.10.059. PMID: 29117563; PMCID: PMC5726784.

Fontes-Garfias CR, Shan C, Luo H, Muruato AE, Medeiros DBA, Mays E, Xie X, Zou J, Roundy CM, Wakamiya M, Rossi SL, Wang T, Weaver SC, Shi PY. Functional Analysis of Glycosylation of Zika Virus Envelope Protein. Cell Rep. 2017 Oct 31;21(5):1180-1190. doi: 10.1016/j.celrep.2017.10.016. PMID: 29091758; PMCID: PMC5708593.

Shan C, Muruato AE, Jagger BW, Richner J, Nunes BTD, Medeiros DBA, Xie X, Nunes JGC, Morabito KM, Kong WP, Pierson TC, Barrett AD, Weaver SC, Rossi SL, Vasconcelos PFC, Graham BS, Diamond MS, Shi PY. A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nat Commun. 2017 Sep 22;8(1):676. doi: 10.1038/s41467-017-00737-8. PMID: 28939807; PMCID: PMC5610254.

Azar SR, Roundy CM, Rossi SL, Huang JH, Leal G, Yun R, Fernandez-Salas I, Vitek CJ, Paploski IAD, Stark PM, Vela J, Debboun M, Reyna M, Kitron U, Ribeiro GS, Hanley KA, Vasilakis N, Weaver SC. Differential Vector Competency of Aedes albopictus Populations from the Americas for Zika Virus. Am J Trop Med Hyg. 2017 Aug;97(2):330-339. doi: 10.4269/ajtmh.16-0969. PMID: 28829735; PMCID: PMC5544086.

Zhao Z, Yang M, Azar SR, Soong L, Weaver SC, Sun J, Chen Y, Rossi SL, Cai J. Viral Retinopathy in Experimental Models of Zika Infection. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):4355–4365. doi: 10.1167/iovs.17-22016. Erratum in: Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4799. PMID: 28810265; PMCID: PMC5558627.

Richner JM, Jagger BW, Shan C, Fontes CR, Dowd KA, Cao B, Himansu S, Caine EA, Nunes BTD, Medeiros DBA, Muruato AE, Foreman BM, Luo H, Wang T, Barrett AD, Weaver SC, Vasconcelos PFC, Rossi SL, Ciaramella G, Mysorekar IU, Pierson TC, Shi PY, Diamond MS. Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease. Cell. 2017 Jul 13;170(2):273-283.e12. doi: 10.1016/j.cell.2017.06.040. PMID: 28708997; PMCID: PMC5546158.

Aliota MT, Bassit L, Bradrick SS, Cox B, Garcia-Blanco MA, Gavegnano C, Friedrich TC, Golos TG, Griffin DE, Haddow AD, Kallas EG, Kitron U, Lecuit M, Magnani DM, Marrs C, Mercer N, McSweegan E, Ng LFP, O'Connor DH, Osorio JE, Ribeiro GS, Ricciardi M, Rossi SL, Saade G, Schinazi RF, Schott-Lerner GO, Shan C, Shi PY, Watkins DI, Vasilakis N, Weaver SC. Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network. Antiviral Res. 2017 Aug;144:223-246. doi: 10.1016/j.antiviral.2017.06.001. Epub 2017 Jun 6. PMID: 28595824; PMCID: PMC5920658.

Langsjoen RM, Auguste AJ, Rossi SL, Roundy CM, Penate HN, Kastis M, Schnizlein MK, Le KC, Haller SL, Chen R, Watowich SJ, Weaver SC. Host oxidative folding pathways offer novel anti-chikungunya virus drug targets with broad spectrum potential. Antiviral Res. 2017 Jul;143:246-251. doi: 10.1016/j.antiviral.2017.04.014. Epub 2017 Apr 28. PMID: 28461071.

Roundy CM, Azar SR, Rossi SL, Weaver SC, Vasilakis N. Insect-Specific Viruses: A Historical Overview and Recent Developments. Adv Virus Res. 2017;98:119-146. doi: 10.1016/bs.aivir.2016.10.001. Epub 2016 Nov 17. PMID: 28433051.

Shan C, Muruato AE, Nunes BTD, Luo H, Xie X, Medeiros DBA, Wakamiya M, Tesh RB, Barrett AD, Wang T, Weaver SC, Vasconcelos PFC, Rossi SL, Shi PY. A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models. Nat Med. 2017 Jun;23(6):763-767. doi: 10.1038/nm.4322. Epub 2017 Apr 10. PMID: 28394328; PMCID: PMC6276361.

Roundy CM, Azar SR, Rossi SL, Huang JH, Leal G, Yun R, Fernandez-Salas I, Vitek CJ, Paploski IA, Kitron U, Ribeiro GS, Hanley KA, Weaver SC, Vasilakis N. Variation in Aedes aegypti Mosquito Competence for Zika Virus Transmission. Emerg Infect Dis. 2017 Apr;23(4):625-632. doi: 10.3201/eid2304.161484. Epub 2017 Apr 15. PMID: 28287375; PMCID: PMC5367433.

McGrath EL, Rossi SL, Gao J, Widen SG, Grant AC, Dunn TJ, Azar SR, Roundy CM, Xiong Y, Prusak DJ, Loucas BD, Wood TG, Yu Y, Fernández-Salas I, Weaver SC, Vasilakis N, Wu P. Differential Responses of Human Fetal Brain Neural Stem Cells to Zika Virus Infection. Stem Cell Reports. 2017 Mar 14;8(3):715-727. doi: 10.1016/j.stemcr.2017.01.008. Epub 2017 Feb 16. PMID: 28216147; PMCID: PMC5355569.

Yang Y, Shan C, Zou J, Muruato AE, Bruno DN, de Almeida Medeiros Daniele B, Vasconcelos PFC, Rossi SL, Weaver SC, Xie X, Shi PY. A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine. EBioMedicine. 2017 Mar;17:145-156. doi: 10.1016/j.ebiom.2017.02.003. Epub 2017 Feb 6. PMID: 28196656; PMCID: PMC5360567.

Xie X, Yang Y, Muruato AE, Zou J, Shan C, Nunes BT, Medeiros DB, Vasconcelos PF, Weaver SC, Rossi SL, Shi PY. Understanding Zika Virus Stability and Developing a Chimeric Vaccine through Functional Analysis. mBio. 2017 Feb 7;8(1):e02134-16. doi: 10.1128/mBio.02134-16. PMID: 28174309; PMCID: PMC5296601.

Jupatanakul N, Sim S, Angleró-Rodríguez YI, Souza-Neto J, Das S, Poti KE, Rossi SL, Bergren N, Vasilakis N, Dimopoulos G. Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus. PLoS Negl Trop Dis. 2017 Jan 12;11(1):e0005187. doi: 10.1371/journal.pntd.0005187. PMID: 28081143; PMCID: PMC5230736.

Hart CE, Roundy CM, Azar SR, Huang JH, Yun R, Reynolds E, Leal G, Nava MR, Vela J, Stark PM, Debboun M, Rossi S, Vasilakis N, Thangamani S, Weaver SC. Zika Virus Vector Competency of Mosquitoes, Gulf Coast, United States. Emerg Infect Dis. 2017 Mar;23(3):559-560. doi: 10.3201/eid2303.161636. Epub 2017 Mar 15. PMID: 28005002; PMCID: PMC5382747.


2016

Erasmus JH, Auguste AJ, Kaelber JT, Luo H, Rossi SL, Fenton K, Leal G, Kim DY, Chiu W, Wang T, Frolov I, Nasar F, Weaver SC. A chikungunya fever vaccine utilizing an insect-specific virus platform. Nat Med. 2017 Feb;23(2):192-199. doi: 10.1038/nm.4253. Epub 2016 Dec 19. PMID: 27991917; PMCID: PMC5296253.

Erasmus JH, Rossi SL, Weaver SC. Development of Vaccines for Chikungunya Fever. J Infect Dis. 2016 Dec 15;214(suppl 5):S488-S496. doi: 10.1093/infdis/jiw271. PMID: 27920179; PMCID: PMC5137239.

Barrows NJ, Campos RK, Powell ST, Prasanth KR, Schott-Lerner G, Soto-Acosta R, Galarza-Muñoz G, McGrath EL, Urrabaz-Garza R, Gao J, Wu P, Menon R, Saade G, Fernandez-Salas I, Rossi SL, Vasilakis N, Routh A, Bradrick SS, Garcia-Blanco MA. A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection. Cell Host Microbe. 2016 Aug 10;20(2):259-70. doi: 10.1016/j.chom.2016.07.004. Epub 2016 Jul 28. PMID: 27476412; PMCID: PMC4993926.

Guerbois M, Fernandez-Salas I, Azar SR, Danis-Lozano R, Alpuche-Aranda CM, Leal G, Garcia-Malo IR, Diaz-Gonzalez EE, Casas-Martinez M, Rossi SL, Del Río-Galván SL, Sanchez-Casas RM, Roundy CM, Wood TG, Widen SG, Vasilakis N, Weaver SC. Outbreak of Zika Virus Infection, Chiapas State, Mexico, 2015, and First Confirmed Transmission by Aedes aegypti Mosquitoes in the Americas. J Infect Dis. 2016 Nov 1;214(9):1349-1356. doi: 10.1093/infdis/jiw302. Epub 2016 Jul 19. PMID: 27436433; PMCID: PMC5079363.

Rossi SL, Vasilakis N. Modeling Zika Virus Infection in Mice. Cell Stem Cell. 2016 Jul 7;19(1):4-6. doi: 10.1016/j.stem.2016.06.009. PMID: 27392219.

Shan C, Xie X, Muruato AE, Rossi SL, Roundy CM, Azar SR, Yang Y, Tesh RB, Bourne N, Barrett AD, Vasilakis N, Weaver SC, Shi PY. An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors. Cell Host Microbe. 2016 Jun 8;19(6):891-900. doi: 10.1016/j.chom.2016.05.004. Epub 2016 May 16. PMID: 27198478; PMCID: PMC5206987.

Rossi, S. L., Tesh, R. B., Azar, S. R., Muruato, A. E., Hanley, K. A., Auguste, A. J., Langsjoen, R. M., Paessler, S., Vasilakis, N., & Weaver, S. C. (2016). Characterization of a Novel Murine Model to Study Zika Virus. The American journal of tropical medicine and hygiene, 94(6), 1362–1369. https://doi.org/10.4269/ajtmh.16-0111


2015

Plante KS, Rossi SL, Bergren NA, Seymour RL, Weaver SC. Extended Preclinical Safety, Efficacy and Stability Testing of a Live-attenuated Chikungunya Vaccine Candidate. PLoS Negl Trop Dis. 2015 Sep 4;9(9):e0004007. doi: 10.1371/journal.pntd.0004007. PMID: 26340754; PMCID: PMC4560411.