Ghulam Ahmad Shakeel Ansari, PhD

Departments of Pathology and
Biochemistry & Molecular Biology,
Co-Director, Integrative Health Science Facility Core, National Institute for Environmental Health & Sciences Center,
Member, Sealy Center for Environmental Health and Medicine

Phone: (409) 772-3107
Fax: (409) 772-9679
Office: (409) 772-3655
Fax: (409) 747-1763

Ghulam Ahmad Shakeel Ansari, PhD

    • Molecular Toxicology
    • Biomarker Signatures
    • Metabolomics
    • Chemical-mediated Autoimmunity
    • Chemical-mediated Liver Injury
    • Systems Biology
  • BS Aligarh Muslim University, Aligarh, India Chemistry 1966
    MS Aligarh Muslim University, Aligarh, India Chemistry 1969
    PhD Aligarh Muslim University, Aligarh, India Chemistry 1973
  • 1992-Present Associate Editor, Bulletin of Environmental Contamination and Toxicology
    2000 Co-Chaired a session entitled, “Cellular Toxicity” at 3rd WorldCongress on Cellular and Molecular Biology, Jena, Germany
    2003 Received “Researcher of the year” award from Department of Pathology, UTMB
    2007-Present Issue Editor, Encyclopedia of Environmental Health
    Editorial Boards
    1988-Present Journal of Toxicology and Environmental Health
    2000-Present Toxicology and Applied Pharmacology
  • 1975-Present American Chemical Society
    1985-Present American Society of Biochemistry and Molecular Biology*
    1985-Present Society of Toxicology*
    1989-Present International Society for the Study of Xenobiotics*
    2008-Present Association for study of Lime Disease
    1. Cai, P., Konig, R., Boor, P. J., Kondragant, S., Kaphalia, B.S., Khan, M.F., Ansari, G.A.S. Chronic exposure to trichloroethene causes early onset of SLE-like disease in female MRL +/+ mice. Toxicol. Appl. Pharmacol. 228:68-75, 2008.
    2. Konig, R., Cai, P., Guo, X., Ansari, G.A.S. Transcription analysis reveals early signs of liver toxicity in female MRL/mice exposed to the acylating chemicals dichloroacetyl chloride and dichloroacetic anhydride. J. Chem. Res. Toxicol. 21:572-582, 2008.
    3. Cai, P., König, R., Khan, M.F., Kaphalia, B.S., Ansari, G.A.S. Differential immune responses to albumin adducts of reactive intermediates of Trichloroethene in MRL +/+ mice. Toxicol. Appl. Pharmacol. 220:278-283, 2007.
    4. Wu, H., Cai, P., Clemens, D.L., Jerrells, T.R., Ansari, G.A.S., Kaphalia, B.S. Metabolic basis of ethanol induced cytotoxicity in recombinant HepG2 cells: Role of nonoxidative metabolism. Toxicol. Appl. Pharmacol. 216:238-247, 2006.
    5. Sharma, R., Ansari, G.A.S. and Awasthi, Y.C. Physiological substrates of glutathione S-transferases. “Toxicology of Glutathione Transferases,” Chapter 9 (Y.C. Awasthi, Editor), CRC Press (2006).
    6. Cai P., Kaphalia, B.S., Ansari, G.A.S. Methyl palmitate: Inhibitor of phgocytosis in primary rat Kupffer Cells. Toxicology, 210:197-204, 2005.
    7. Mericle, K.A., Kaphalia, B.S., Ansari, G.A.S. Modulation of fatty acid methyl esters in rats pre-treated with tri-o-tolyl phosphate. J. Toxicol. Environ. Health, Part A 67:583-593, 2004.
    8. Green, S.M., Khan, M.F., Kaphalia, B.S., Ansari, G.A.S. Immnohistochemical localization of protein adducts of tetrachloreoethene in mice. J. Toxicol. Environ. Health 63: 145-157, 2001.
    9. Kaphalia BS, Fritz RR and Ansari GAS. Purification and characterization of rat liver microsomal fatty acid ethyl and 2-chloroethyl ester synthase and their relationship with carboxylesterase (Pl 6.1). Chem. Res. Toxicol. 10:211-218, 1997.
    10. Awasthi YC, Zimniak P, Awasthi S, Singhal SS, Srivastava SK, Piper JT, Chaubey M, Petersen DR, He N, Sharma R, Singh SV, Khan FM, Ansari GAS, Boor PJ. A new group of glutathione S-transferase with protective role against lipid peroxidation. Glutathione s-transferases: structure, function and clinical implications. (Vermeulen et al., editors; Taylorand Francis, 1996) pages 111-124.
    11. Ansari GAS, Kaphalia BS, Khan MF. Fatty acid conjugates of xenobiotics. (invited review) Toxicol Lett 75:1-17, 1995.
      Kaphalia BS, Carr JB, Ansari GAS. Increased endobiotic fatty acid methyl esters following exposure to methanol. Fundam Appl Toxicol. 28:264-273, 1995.
    12. Khan MF, Kaphalia BS, Prabhakar BS, Kanz MF, Ansari GAS. Trichloroethene - induced autoimmune response in female MRL +/+ mice. Toxicol Appl Pharmacol 134:155-160, 1995.
    13. Ansari GAS, Smith LL. Assay of cholesterol oxidation. Methods Enzymol. 233: 332-338, 1994.
      Kanz MF Kaphalia L, Kaphalia BS, Ramagnoli E, Ansari GAS. Methylene dianiline: Acute toxicity and effect on biliary function. Toxicol. Appl. Pharmacol. 117:89-92, 1992.
    14. Boor PJ, Khan MF, Kaphalia BS, Jerrells TR, Ansari GAS. Synergistic vascular toxicity and fatty acid anilides in the toxic oil syndrome. J Am Coll Cardio 18: 1824-1828; 1991.
    15. Bhat HK, Ansari GAS. Cholesterol ester hydrolase mediated conjugation of haloethanols with fatty acids. Chem Res Toxicol 3: 311-317;1990.
    16. Ansari GAS, Kaphalia BS, Boor PJ. Selective pancreatic toxicity of palmitoylpentachlorophenol. Toxicology 46: 57-63; 1987.
    17. Ansari GAS, Smith LL. High performance liquid chromatography of cholesterol autoxidation products. J Chromatogr 175: 307-315; 1979.
    18. Ahmad MS, Ansari GAS. Mass spectral studies on steroidal compounds-I, steroidal 6-one ethylene acetals. Org Mass Spectrom 6: 1095-1108; 1973.

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