Vsevolod Leonidovich Popov

Vsevolod Leonidovich Popov, PhD, DSc

Department of Pathology
Director, Electron Microscopy Laboratory
Center for Biodefense and Emerging Infectious Diseases
World Reference Center for Emerging Viruses and Arboviruses
Institute for Human Infections and Immunity

Phone: (409) 747-2423
Email: vpopov@utmb.edu

Vsevolod Leonidovich Popov, PhD, DSc

  • My area of expertise is ultrastructural studies of bacteria (especially rickettsia, ehrlichia, anaplasma, and chlamydia), viruses and protozoa pathogenic for humans and animals and their interaction with the host cells at the ultrastructural level in patients and in model systems. I have more than 50 years of experience in electron microscopy and its different techniques. My expertise in this area is documented in more than 250 publications in peer-reviewed journals. During these years I have collaborated with many investigators nationally and internationally and trained more than 70 graduate students, fellows and research scientists in electron microscopy techniques, analysis and interpretation of electron microscopic data.
  • ScD (DSc) N.F. Gamaleya Epidemiology & Microbiology Institute, Moscow Microbiology 1985
    PhD N.F. Gamaleya Epidemiology & Microbiology Institute, Moscow, Russia, USSR Microbiology 1969
    M.Sc M.V. Lomonosov Moscow State University, Moscow, Russia, USSR Vertebrate Zoology and Anatomy 1964
    2011 Graduate School of Biomedical Sciences Teaching Excellence Award in Experimental Pathology
    2011 Researcher of the Year, Department of Pathology, UTMB, in Recognition of Outstanding Scientific Investigations and Dedicated University Service
    2009 Nominated for Charles C. Shepard Award (Laboratory and Methods) at CDC for demonstrating excellence in Science as a co-author of the paper "Bartonella tamiae sp. nov., a newly recognized pathogen isolated from three human patients from Thailand".
    2005 Experimental Pathology Graduate Student Organization Award for Excellence in Graduate Teaching and Mentoring
    1980 Excellence of the USSR Ministry of Health
  • Other Experience and Professional Memberships
    2004-2012 Society for General Microbiology (Great Britain)
    1995- American Society of Tropical Medicine and Hygiene
    1994- Electron Microscopy Society of America, (now Microscopy Society of America)
    1993- American Society for Microbiology
    1991 - American Society for Rickettsiology
  • Updated CV (Word)

    1. Popov VL, Han VC, Chen S-M, Dumler JS, Feng H-M, Andreadis TG, Tesh RB, Walker DH. Ultrastructural differentiation of the genogroups in the genus Ehrlichia. J Med Microbiol. 47: 1-17, 1998.
    2. Qi H, Popov V, Soong L. Leishmania amazonensis-dendritic cell interactions in vitro and the priming of parasite-specific CD4+ T cells in vivo. J Immunol, 167:4534-4542, 2001.
    3. Langer RC, Li F, Popov V, Kurosky A, Vinetz JM. Monoclonal antibody against the Plasmodium falciparum chitinase, PfCHT1, recognizes a malaria transmission-blocking epitope in Plasmodium gallinaceum ookinetes unrelated to the chitinase PgCHT1. Infect Immun. 70(3):1581-1590, 2002.
    4. Martin A, Bodola F, Sangar D, Goettge K, Popov V, Rijnbrand R, Lanford R, Lemon S. Chronic hepatitis associated with GB virus B persistence in a tamarin after intrahepatic inoculation of synthetic viral RNA. PNAS, 100(17):9962-9967, 2003.
    5. Stenos J, Graves S, Popov VL, Walker DH. Aponomma hydrosauri, the reptile-associated tick reservoir of Rickettsia honei on Flinders Island, Australia. Amer J Trop Med Hyg, 63(3):314-317, 2003.
    6. Draghi II A, Popov VL, Kahl MM, Stanton JB, Brown CC, Tsongalis GJ, West AB, Frasca Jr S. Characterization of “Candidatus Piscichlamydia salmonis” (Order Chlamydiales), a chlamydia-like bacterium associated with epitheliocystis in farmed atlantic salmon (Salmo salar). J Clin Microbiol, 42(11): 5286-5297, 2004.
    7. Labruna MB, Whitworth T, Bouyer DH, McBride J, Camargo LMA, Camargo EP, Popov V, Walker DH. Rickettsia bellii and Rickettsia amblyommii in Amblyomma ticks from the state of Rondonia, Western Amazon, Brazil. J Med Entomol, 41(6):1073-1081, 2004.
    8. Doyle CK, Nethery KA, Popov VL, McBride JW. Differentially expressed and secreted major immunoreactive protein orthologs of Ehrlichia canis and E. chaffeensis elicit early antibody responses to epitopes on glycosylated tandem repeats. Infect Immun, 74(1) :711-720, 2006.
    9. Zhang J, Popov VL, Gao S, Walker DH, Yu X. The developmental cycle of Ehrlichia chaffeensis in vertebrate cells. Cellular Microbiol, 9:610-618, 2007 (first published online 20 Sept. 2006).
    10. Överby AK, Popov VL, Neve EPA, Pettersson RF. Generation and analysis of infectious virus-like particles of Uukuniemi virus (Bunyaviridae) : a useful system for studying bunyaviral packaging and budding. J Virol, 80,21 :10428-10435, 2006.
    11. McBride JW, Doyle CK, Zhang X, Cardenas AM, Popov VL, Nethery KA, Woods ME. Identification of a glycosylated Ehrlichia canis 19-kilodalton major immunoreactive protein with a species-specific serine-rich glycopeptide epitope. Infect Immun,75,1 :74-82, 2007.
    12. Girard YA, Schneider BS, McGeeCE, Wen J, Han VC, Popov V, Mason PW, Higgs S. Salivary gland morphology and virus transmission during long-term cytopathologic West Nile virus infection in Culex mosquitoes. Amer J Trop Med Hyg, 76,1 :118-128, 2007.
    13. Draghi A, Bebak J, Popov VL, Noble AC, Geary SJ, West AB, Byrne P, Frasca S. Characterization of a Neochlamydia-like bacterium associated with epitheliocystis in cultured Arctic charr Salvelinus alpinus. Dis Aquat Org, 76 :27-38, 2007.
    14. 62. Popov VL, Korenberg EI, Nefedova VV, Han VC, Wen JW, Kovalevskii YV, Gorelova NB, Walker DH. Ultrastructural evidence of ehrlichial developmental cycle in naturally infected Ixodes persulcatus ticks in the course of coinfection with rickettsia, borrelia, and a flavivirus. Vector-Borne Zoonot Dis, 7:699-716, 2007.
    15. Luo T, Zhang X, Wakeel A, Popov VL, McBride JW. Variable-length PCR target protein of Ehrlichia chaffeensis contains major species-specific antibody epitopes in acidic serine-rich tandem repeats. Infect Immun, 76,4:1572-1580, 2008.
    16. Macaluso KR, Pornviroon W, Popov VL, Foil LD. Identification of Rickettsia felis in the salivary glands of cat fleas. Vector-Borne Zoonot Dis, 8,3:391-396, 2008.
    17. Goluszko P, Popov V, Wen J, Jones A, Yallampalli C. Group B streptococcus exploits lipid rafts and phosphoinositide 3-kinase/Akt signaling pathway to invade human endometrial cells. Am J Obstet Gynecol, 199,5:548.e1-9, 2008.
    18. Kozlova EV, Popov VL, Sha J, Foltz SM, Erova TE, Agar SL, Horneman AJ, Chopra AK. Mutation in the S-ribosylhomocysteinase (luxS) gene involved in quorum sensing affects biofilm formation and virulence in a clinical isolate of Aeromonas hydrophila. Microbial Pathog, 45:343-354, 2008.
    19. Kim DY, Guzman H, Bueno Jr R, Dennett JA, Auguste AJ, Carrington CVF, Popov VL, Weaver SC, Beasley DWC, Tesh RB. Characterization of Culex Flavivirus (Flaviviridae) strains isolated from mosquitoes in the United States and Trinidad. Virology, 386:154-159, 2009.
    20. Duh D, Punda-Polic V, Avsic-Zupanc T, Bouyer D, Walker DH, Popov VL, Jelovsek M, Gracner M, Trilar T, Bradaric N, Kurtti TJ, Strus J. Rickettsia hoogstraalii sp. nov., isolated from hard- and soft-bodied ticks. Int J Syst Evol Microbiol, 2009, Epub ahead of print Aug 7.

    NIH Biosketch