Lung Tissue

Research ProgramsMichael Laposata, MD, PhD

Diagnostic Management Autopsy


Research Teaching & Mentoring

Research Activities

Areas of Research

2014 –Diagnostic errors in medicine
1999 – 2015Fatty acid alterations in cystic fibrosis
1994 – 2005Fatty acid ethyl esters, nonoxidative ethanol metabolites
1989 – 1993Fatty acid acylation of platelet proteins
1985 – 1994Fatty acids and fatty acid metabolites in cell activation

Grant Support

1986 – 1995R01 DK37454—National Institutes of Health
Control of Icosanoid Precursor Fatty Acid Metabolism
1987 – 1988Sheryl N. Hirsch Award of the Lupus Foundation of Philadelphia
Direct Costs: $10,000
1990 – 1993R01 DK43159—National Institutes of Health
Extracellular Fatty Acid Supply and Icosanoid Production
1994 – 2008Funding from clinical revenue at Massachusetts General Hospital of basic research program
Annual Direct Costs: $70,000–111,000
2006Cystic Fibrosis Foundation
Determining the Role of Fatty Acids and Diet in Cystic Fibrosis
Co–Principal Investigator
Co–PI Annual Direct Costs: $250,000
2008Center for Minimally Invasive Therapy "Lab-In-A-Box"
Project Development
Principal Investigator
$28,000 (Declined because of move to Vanderbilt)
2008 – 2011Funding from Vanderbilt University School of Medicine of basic research program
Annual Direct Costs: $120,000
2010 – 2015Funding from Endowed Chair directed to research program
Annual Direct Costs: $80,000
2011 – 2013Project Title: Pharmacogenomic Resource for Enhanced Decisions in Clopidogrel Treatment (PREDICT)
Principal Investigator: Michael Laposata
Grant Number: 1U47CI000824–01
Project Period: 09/30/2011–09/29/2013
Total Direct Costs: $499,013 annually for 2 years
2011 – 2012Project Title: Proactive Risk Assessment during the Clinical Laboratory Testing Process to Reduce Diagnostic Error– AHRQ RFTO No. 2
Principal Investigator: Dr. Mark Graber, RTI International
Dr. Michael Laposata, Principal Investigator for Vanderbilt subcontract and member of technical expert panel
Project Period: 07/01/2011–12/31/2012
Total Direct Costs: $45,050 for subcontract effort and $415,323 overall