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Faculty Members of the IHII (M - R)

Members of the Institute for Human Infections & Immunity are University of Texas Medical Branch faculty actively engaged in the study of infectious diseases and immunity.

Alphabetical Listing of IHII Members: A - C  |  D - L  |  M - R  |  S - Z

Shinji Makino, DVM, PhD

Pathogenesis, vaccine development, virology
View Department of Microbiology & Immunology profile We study various aspects of SARS coronavirus-host cell interactions, attempting to understand viral pathogenesis at the molecular level. We also study viral RNA synthesis, assembly, virus-host cell interactions and vaccine development of Rift Valley fever virus, which is highly pathogenic for humans and ruminants.
IHII center affiliations: CBEID, CTD, SCVD

C. Glen Mayhall, MD

View Department of Internal Medicine profile I am the Healthcare Epidemiologist for the UTMB Health System and a member of the faculty in the Division of Infectious Diseases. My research interests include prevention of healthcare-associated infections in burn patients, prevention of healthcare-associated infections caused by Clostridium difficile in hospitalized patients, and prevention and control of antimicrobial resistance.

Jere McBride, PhD

Cellular microbiology, bacteriology, immunology, pathobiology/pathogenesis, diagnostic/vaccine development
View Department of Pathology profile Identification and molecular characterization of protective immunodeterminants of Ehrlichia spp., investigation of pathogenic mechanisms and host-pathogen interactions of Ehrlichia, understanding the molecular mechanisms in the adaptation of Ehrlichia to mammalian and arthropod hosts, and translational research on development of diagnostics and vaccines for the ehrlichioses.
IHII center affiliations: CBEID, CTD, SCVD




Vladimir Motin, PhD

Bacteriology, pathogenesis, vaccine development, systems biology
View Department of Pathology profile My major research interest is to elucidate the molecular mechanisms that underlie the nature of the acute bacterial infectious process caused by Y. pestis, the etiological agent of plague. The unraveling of Y. pestis virulence network will allow us to determine novel targets for therapeutics beyond antibiotics, generation of new vaccines and for development of robust diagnostic assays.
IHII center affiliations: CBEID, CTD, SCVD

Frederick Murphy, DVM, PhD

Virology
View Department of Pathology profile Dr. Murphy's professional interests include the virology, pathology and epidemiology of highly pathogenic viruses/viral diseases. He has been a leader in advancing the concept of "new and emerging infectious diseases" and "new and emerging zoonoses," which has reinvigorated and reenergized the infectious disease sciences. Most recently his interests have included the threat posed by bioterrorism.
IHII center affiliations: CBEID, CTD



David Niesel, PhD

View Department of Microbiology & Immunology profile We are investigating Streptococcus pneumoniae gene/protein expression changes in vivo and in low shear microgravity environments. We have had multiple experiments performed on the space shuttle and on the International Space Station. The laboratory is also developing rapid novel methods for antibiotic resistance detection in complex populations of bacteria.

Juan Olano, MD

Bacteriology, anatomic and clinical pathology, endothelial pathology, pathogenesis
View Department of Pathology profile My research interests are focused on the pathogenesis of obligate intracellular bacteria. My long term goal is to study molecular pathogenesis of rickettsioses. I am interested in adherens- and tight junction proteins and the signal transduction pathways involved in their regulation. Another area of focus is the development of ultrasensitive diagnostic methods for rickettsial infections and the development of small animal models.
IHII center affiliations: CBEID, CTD, SCVD

Andres Oberhauser, PhD

View Department of Neuroscience & Cell Biology profile My research focuses on the dynamics and mechanics of proteins using single-molecule manipulation techniques. My laboratory has developed methods to investigate the effect of disease-causing mutations on the nano-mechanics of muscle and kidney protein complexes. We are also using AFM-based nano-mechanical studies in living cells infected with Rickettsiae montanensis.

Slobodan Paessler, DVM, PhD

View Department of Pathology profile

Janak Patel, MD

View Department of Pediatrics profile I am engaged in clinical practice of pediatric infectious diseases. My research interest is in the study of respiratory viral epidemiology, host response and complications leading to acute otitis media in children. The roles of host genes of innate immunity, cytokines and viral-bacterial interactions in the nasopharynx are also being studied.



Vsevolod Popov, PhD, DSc

Bacteriology, pathogenesis, structural biology/imaging, electron microscopy, virology
View Department of Pathology profile My research interests include ultrastructure of bacteria (especially rickettsia, ehrlichia, anaplasma, and chlamydia), viruses and protozoa pathogenic for humans and animals and their interaction with the host cells at the ultrastructural level in patients and in model systems.
IHII center affiliations: CBEID, CTD

Don Powell, MD

Immunology, clinical, structural biology/imaging, host response
View Department of Internal Medicine profile My research interests currently include the biology of intestinal mesenchymal cells, including their role in the colon cancer microenvironment and their immunological role in promoting immune tolerance or in the pathophysiology of inflammatory bowel disease and the response to infection.
IHII center affiliations: CTD


Krishna Rajarathnam, PhD

Immunology, structural biology, protein engineering
View Department of Biochemistry & Molecular Biology profile Chemokine-mediated recruitment of circulating neutrophils to the site of infection forms the first line in host defense. My research focuses on understanding the molecular mechanisms by which chemokines (such as CXCL8) interact with their GPCR receptors and glycosaminoglycans for orchestrating in vivo neutrophil recruitment in health and disease.


Barry Rockx, PhD

Pathogenesis, vaccine development, virology
View Department of Pathology profile My research focuses on Henipaviruses and filoviruses, including mechanisms of transmission and pathogenesis, host-virus interactions, and vaccine development. My research approaches include the development and characterization of novel in vitro and in vivo models. A second area of interest is the development and testing of broadly protective therapeutics.
IHII center affiliations: CBEID, SCVD

Judith Rowen, MD

View Department of Pediatrics profile As a pediatric infectious disease specialist, my particular area of interest is neonatal infections, especially neonatal candidiasis, group B streptococcal infections and nosocomial infections in intensive care nurseries. I serve as the Associate Dean for Educational Affairs for the School of Medicine, so I am currently focused on medical education, and wherever possible like to combine my interests in infectious diseases and education.

 

Alphabetical Listing of IHII Members: A - C  |  D - L  |  M - R  |  S - Z