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Faculty Members of the IHII (M - R)

Members of the Institute for Human Infections & Immunity are University of Texas Medical Branch faculty actively engaged in the study of infectious diseases and immunity.

Alphabetical Listing of IHII Members: A - C  |  D - L  |  M - R  |  S - Z

Shinji Makino, DVM, PhD

Pathogenesis, vaccine development, virology
View Department of Microbiology & Immunology profile We study various aspects of SARS coronavirus-host cell interactions, attempting to understand viral pathogenesis at the molecular level. We also study viral RNA synthesis, assembly, virus-host cell interactions and vaccine development of Rift Valley fever virus, which is highly pathogenic for humans and ruminants.
IHII center affiliations: CBEID, CTD, SCVD


Jere McBride, PhD

Cellular microbiology, bacteriology, immunology, pathobiology/pathogenesis, diagnostic/vaccine development
View Department of Pathology profile Identification and molecular characterization of protective immunodeterminants of Ehrlichia spp., investigation of pathogenic mechanisms and host-pathogen interactions of Ehrlichia, understanding the molecular mechanisms in the adaptation of Ehrlichia to mammalian and arthropod hosts, and translational research on development of diagnostics and vaccines for the ehrlichioses.
IHII center affiliations: CBEID, CTD, SCVD




Vladimir Motin, PhD

Bacteriology, pathogenesis, vaccine development, systems biology
View Department of Pathology profile My major research interest is to elucidate the molecular mechanisms that underlie the nature of the acute bacterial infectious process caused by Y. pestis, the etiological agent of plague. The unraveling of Y. pestis virulence network will allow us to determine novel targets for therapeutics beyond antibiotics, generation of new vaccines and for development of robust diagnostic assays.
IHII center affiliations: CBEID, CTD, SCVD

Frederick Murphy, DVM, PhD

Virology
View Department of Pathology profile Dr. Murphy's professional interests include the virology, pathology and epidemiology of highly pathogenic viruses/viral diseases. He has been a leader in advancing the concept of "new and emerging infectious diseases" and "new and emerging zoonoses," which has reinvigorated and reenergized the infectious disease sciences. Most recently his interests have included the threat posed by bioterrorism.
IHII center affiliations: CBEID, CTD




Juan Olano, MD

Bacteriology, anatomic and clinical pathology, endothelial pathology, pathogenesis
View Department of Pathology profile My research interests are focused on the pathogenesis of obligate intracellular bacteria. My long term goal is to study molecular pathogenesis of rickettsioses. I am interested in adherens- and tight junction proteins and the signal transduction pathways involved in their regulation. Another area of focus is the development of ultrasensitive diagnostic methods for rickettsial infections and the development of small animal models.
IHII center affiliations: CBEID, CTD, SCVD


Slobodan Paessler, DVM, PhD

View Department of Pathology profile




Vsevolod Popov, PhD, DSc

Bacteriology, pathogenesis, structural biology/imaging, electron microscopy, virology
View Department of Pathology profile My research interests include ultrastructure of bacteria (especially rickettsia, ehrlichia, anaplasma, and chlamydia), viruses and protozoa pathogenic for humans and animals and their interaction with the host cells at the ultrastructural level in patients and in model systems.
IHII center affiliations: CBEID, CTD

Don Powell, MD

Immunology, clinical, structural biology/imaging, host response
View Department of Internal Medicine profile My research interests currently include the biology of intestinal mesenchymal cells, including their role in the colon cancer microenvironment and their immunological role in promoting immune tolerance or in the pathophysiology of inflammatory bowel disease and the response to infection.
IHII center affiliations: CTD


Krishna Rajarathnam, PhD

Immunology, structural biology, protein engineering
View Department of Biochemistry & Molecular Biology profile Chemokine-mediated recruitment of circulating neutrophils to the site of infection forms the first line in host defense. My research focuses on understanding the molecular mechanisms by which chemokines (such as CXCL8) interact with their GPCR receptors and glycosaminoglycans for orchestrating in vivo neutrophil recruitment in health and disease.


Barry Rockx, PhD

Pathogenesis, vaccine development, virology
View Department of Pathology profile My research focuses on Henipaviruses and filoviruses, including mechanisms of transmission and pathogenesis, host-virus interactions, and vaccine development. My research approaches include the development and characterization of novel in vitro and in vivo models. A second area of interest is the development and testing of broadly protective therapeutics.
IHII center affiliations: CBEID, SCVD


 

Alphabetical Listing of IHII Members: A - C  |  D - L  |  M - R  |  S - Z